Studies have described the therapeutic role of agmatine. I read many studies about Agmatine and these. Disclaimer: The statement above reflects that of my own opinion & in no way that of MAN Sports. Agmatine is getting some more attention here on the nootropic/supplements/stack advice reddit. It has cured my depression. 3748/wjg. Malta has warned against using a MusclePharm workout supplement endorsed by Arnold Schwarzenegger following an investigation into its agmatine sulphate content concerning a total of 30 countries. And wow. Multi-ingredient performance supplements (MIPS) may be comprised of ingredients such as BCAAs, creatine, beta-alanine, agmatine sulfate, taurine, creatinol-o-phosphate, and a combination of nitrate-containing compounds purported to enhance both acute performance and long-term neuromuscular adaptations [3-5]. As in all cases of contamination, LGC began the investigation process with the brand and manufacturer. The main mechanisms of agmatine were related to inhibition of the adaptation of opioid receptor signal transduction induced by chronic treatment of opioid. Agmatine is effective tolerance reducer, but I’m sure you have heard it can mute the mood lift and euphoria, while increasing the pain relief. It's $200 spend for free shipment or something like $20 DHL if below. Agmatine is commonly used by. In contrast, a bulk powder (such as the agmatine sulfate on this site), you can get 500mg of agmatine for $0. It was not banned for safety reasons, rather some odd EU rule that since it was not sold before 1997, it now needs to go through an approval process, that someone would have to pay for, before it can continue to be sold. 5g. 26–39 Our study reports the in vivo neuroprotective effect of agmatine against ROT-induced dopaminergic neurons toxicity in rats. It reduces anxiety and promotes a sense of well-being. 99 for 2kg. Agmatine is an intermediate in the biosynthesis of the polyamines putrescine and spermine. Taking 3-3. That’s dope. Clinical examinations and laboratory analyses of blood samples revealed no abnormality in any parameter studied in all participants of the trial. Neuroprotective Benefit: Agmatine has some effects in preclinical rodent models of neurodegenerative disease, but human data. This makes a single serving or scoop (15. I've been on it for 3 consecutive months without any noticeable side effects and stopped at some point. Agmatine sulfate Grape seed extract Caffeine: 20 min prior to exercise: Maximum Bodyweight Exercise Repetitions Completed during a 20-min Exercise Bout: ↑ Repetitions Completed (d = 0. What are the benefits of taking Venom?I've read multiple reports that Agmatine Sulfate can drastically improve sleep onset and in general, better overall sleep quality. The safe dosage is considered to be at 75mg or less. drugs under pre-clinical or clinical development or discontinued, designer drugs,. The half life in your blood stream is only 2 hours but the half life in your brain is 24-72 hours, so say 48 hours average or 2 days. Agamatine is an interesting supplement. Agmatine evoked acute itch in mice. N-Acetyl-L-Tyrosine:Agmatine sulfate is decarboxylated L-arginine which is postulated to be a neurotransmitter and neuromodulator with nootropic effects. level 1. My experience with agmatine is that dosage and frequency of dosage is very important. Agmatine is an endogenous polyamine synthesized by the enzyme arginine decarboxylase. It 100% improved symptoms of my depression over the course of several weeks. 1 mM) of. Half and full-sleeve tattoos ARE allowed. Participants diagnosed with painful SFN and autonomic dysfunctions were treated with 2. Agmatine is a metabolite of L-Arginine. Strangely like phenibut, agmatine can also be taken. 3. reporting back as this is the first night I took some agmatine sulfate. Clinical follow-up consists of periodic physical examinations and laboratory blood and urine analyses. Oh, I thought that was why you were saying it wasn't good for people with Bipolar. New to this sub. 81, p < 0. This beats it, by far, and it really has to do with a simple understanding of what happens in anxiety & depression, which in essence is an atrophy of various of parts of the brain. The study below talks about agmatine’s ability to increase efficacy of ssri’s and bupropion by ten fold. If agmatine was administered to hypertensive. Share. The findings also lend support to unpublished observations of hundreds of people who are, on their own cognizance, using. It has been studied for the relief of sciatica (radiating lower back pain). Forma produktu. I just looked into this, and we've really not had any issues shipping Agmatine Sulfate to the UK. Agmatine puts me to sleep and has had no positive effect on confidence/motivation. yourmainmushroom • 1 yr. With 8,000 mg of L-citrulline, 3,000 mg of beta-alanine, 1,500 mg of agmatine sulfate and 120 mg of DMAA, this pump pre-workout gives you a euphoric feeling to push through those hard workouts with full concentration and energy. ) were administered daily. It helps with addiction by tamping down dopamine responses and causing more neuron growth. Evidence for oral agmatine sulfate safety--a 95-day high dosage pilot study with rats. I’ve taken the doses together and various other times of the day. I don't think agmatine feeds it, I have never read that before, but it does create gastrointestinal problems when you take agmatine and you have H. This substance is a miracle and it lowers tolerance to almost all substances like alcohol. It's Non-GMO, Gluten-Free and contains no Artificial Flavor, Artificial Sweetener or Preservatives!Agmatine sulfate. They must also ensure that restricted ingredients are. Recent clinical studies have already shown that oral agmatine sulfate given for up to 3 weeks provides a safe and, as compared with current therapeutics, more effective treatment for neuropathic pain. Tested for banned substances Uses branded ingredients/raw materials Manufactured in an NSF facility that carries both the cGMP and Athletic Banned Substances certifications Uses generic ingredients Uses a proprietary blend Uses stimulants to cover up for insufficient ingredient profile (i. d. There's some people that feel great on agmatine, but it's not for everyone. Malta has warned against using a MusclePharm workout supplement endorsed by Arnold Schwarzenegger following an investigation into its agmatine sulphate content. Creatine or arginine is most popular. So, a couple of examples of appropriate dosages would be: If you weigh 140 lbs, take between 102 to 407 mg per day. It's almost astonishing as to how something so good at reducing tolerance and alleviating withdrawal is almost completely unknown to the average stoner. But I only use it one day per week to save money, and only in one 750mg dose at that. At 17g protein & only 91 calories per 25g. Objective. Structure Search. The results suggest that dietary agmatine sulfate has a significant effect in reducing neuropathic pain intensity associated with painful SFN resistant to treatment. £59. 3 In short, agmatine sulfate, as an endogenous neuromodulator and when taken in supplemental form, increases the activity of neurons associated with the handling of stress, anxiety and. Agmatine is a byproduct of the amino acid arginine, but goes well beyond arginine in terms of benefits. I’ve been taking agmatine 1 gram 2x a day for about a month now. 33) Jagim et al. Agmatine is a popular supplement in the body building community due to its “pump” effect – essentially increasing Nitric Oxide and blood flow. And it has effects on the nervous system, it can help heal traumatic brain injuries and damages from drug use. Pylori a microbe known to impact mood and depression negatively. 50 g. 335 g/day agmatine sulfate for 10 days, 2. $4499 ($3. In addition, agmatine is used in addiction therapy . It is often used in pre-workout supplements. Mix one (1) serving of this dietary supplement with 4-6 ounces of water or your preferred pre-workout beverage 20 minutes before your workout. Melon Berry. Carbohydrates: 5. Here are 4 benefits you might experience when taking agmatine sulfate. 99. Agmatine sulfate is a compound that is a metabolite of Agmatine, a substance formed by processing arginine. 3. Find helpful customer reviews and review ratings for BulkSupplements. Agmatine is a member of biogenic amines and is an important medicine which is widely used to regulate body balance and neuroprotective effects. Agmatine - posseses the same action as ketamine. 📒 Show Notes 📒 I hope you enjoy! "Agmatine Sulfate - My Experience and Review (Updated 2021)"📕 FREE EBOOK - 87+ Ways To Increase Dopamine agmatine sulfate powders or pills generally contain 250-750 mg agmatine sulfate per serving where daily intake can be up to 7500 mg/day. Short half life and not as strong as memantime. Op · 1y. Evidence for oral agmatine sulfate safety--a 95-day high dosage pilot study with rats. Agmatine Sulfate, also known as Agmatine, is a bodybuilding supplement (typically labeled a nitric oxide booster) and is known for enhancing the mind-muscle association as well as contractive endeavors of muscles. Applications Products Services Documents Support. Agmatine, is a substance that has existed since 1911 which posseses the same antidepressant effects as ketamine and other glutamergic drugs, by inducing massive neurogenesis in the prefrontal cortex & hippocampus via mTor signaling and AMPA receptor activation. 5–0. Agmatine has been shown to produce fast antidepressant-like effect by stimulating mechanistic target of rapamycin complex 1. Advanced Search. 5 g in the morning with Kratom, . 8g. @gbny1224 where did you get agmatine from? My understanding is that it is banned at the moment pending further research. LGC/R/2016/535Agmatine sulfate | C5H16N4O4S | CID 2794990 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities. I am back down to 5-7 grams of kratom 3-4 times a day with good pain control. 25. There are long term large scale human studies showing agmatine to be "safe". According to several reports and studies, agmatine naturally reverses pain from factors like inflammation, neuropathy and spinal. 425 grams) around $1. This article will explore the uses, side effects of agmatine sulfate supplements and its interactions with other drugs. 1. Agmatine, in some ways, counteract some arginine effects and the latter is known to relax blood vessels, lowering blood pressure as a result. It‘s. However, I recently tried a combination of, two times per week, 1g Agmatine Sulfate and 1g Magnesium L-Threonate before bed, and let me tell you: the next morning, I feel absolutely no need to take the modafinil and coffee combo. Citrulline Malate and nitrates is what you need. I can‘t find certain answers on this. 1 Introduction. Don't use Citrulline with Agmatine. A daily dose of 2. 10% off first order. The research is still minimal. To ascertain agmatine transport. Protein: 35g. Sodium sulfate: The therapeutic. This makes agmatine sulfate a popular pump-inducing ingredient, but further research is necessary. I never got any pumps from it but it has a ton of other benefits. Structurally, Agmatine Sulfate is a polycation at physiological pH, possessing four potential hydrogen acceptor groups and three potential. All drugs were dissolved in 0. Louis, MO). Fat: 3. Hi guys, I was reading a while back about a supplement called "agmatine sulfate" (specifically on its ability to potentiate the effects of cannabis on the CB1 receptors). Agmatine sulfate salt has been used: to study its effects on nod-like receptor protein 3 (NLRP3) inflammasome activation and cytokine responses in sub-chronic restraint stress rat models; as an N-methyl-D-aspartate (NMDA) receptor blocker to study its therapeutic effects on autistic behaviors in the valproic acid-induced animal model of autism; as a standard. This is just a brief overview of what agmatine sulfate, as a supplement, can. , 2020; Rogers et al. You can use either I guess but studies have been done on. I’m guessing the opioid-like effects might blunt or dull the uplifting side of kratom. Best time to take agmatine sulfate. Agmatine Sulphate. Buy it here. Introduction. It also has research for depression, and some use it as a nootropic for focus and cognitive function. Horbaach's Agmatine Sulfate Supplement: We test our nutrients to ensure purity, potency and excellence. i. Betaine anhydrous helps the body to process a. J. 6-8g of cit mal. Dosages range between 250 mg to 1,000 mg per scoop, with intake. Arginine (and by extension, citrulline) are inhibitory to some of the neurological effects of agmatine supplementation such as reducing opioid tolerance. $2350 ($1. TL;DR, agmatine doesn't potentiate nicotine but it prevents a tolerance building up, resulting in the need for less nicotine over time to achieve the same results as more nicotine without agmatine. I like it. L-Citrulline DL-Malate 2:1 Powder. This substance, among others prevents tolerance and addiction to morphine by activating imidazole receptors. Agmatine Sulfate. At a time where DMAA is hard to find, expensive and almost banned from being sold, Anti Hero Labs is not one to hide. I have been using phenibut for about a year. 12 Agmatine reduces infarct area in a mouse model of. But the plaque risk with bromantane is way overblown. But I personally experienced tolerance eventually. I am a bot, and this action was performed automatically. Caffeine Matrix: Caffeine Anhydrous, Infinergy (Dicaffeine Malate), Caffeine Citrate. 1. Molecular Weight 228. oernlind • 3 yr. One participant of the 3rd cohort. Puya Yazdi, MD | Written by Joe Cohen, BS | Last updated: August 15, 2023 Agmatine is a compound naturally produced within the body that plays a key role in a. ago. Agmatine Sulfate (C 5 H 14 N 4) is a biogenic amine, synthesized in the brain through the decarboxylation of the amino acid L-arginine, a process mediated by the enzyme arginine decarboxylase. 500-1000mg of agmatine. If you weigh 200 lbs, take between 145 to 581 mg per day. Agmatine sulfate. Agmatine banned in EU and UK? If so, why is agmatine illegal in the EU and UK. e. Edwards. C. pred tréningom s 200-250ml vody. Never tried it to try and save money or use less CBD as agmatine is pretty expensive on its own. 1). Herein, we investigated the effects of agmatine on systolic blood pressure (SBP), nitric oxide (NO)-mediated endothelium-dependent and -independent vasorelaxant responses in thoracic aorta, cognitive performance (passive avoidance test; PAT, and. juliusdrdre • 3 yr. It has been studied for the relief of sciatica (radiating lower back pain). In this study, the antidepressant-like action of agmatine administered p. Agmatine saved my life. NCATS GSRS Full Record. Personally, the most I noticed from agmatine was that I became more sensitive to caffeine. This makes agmatine sulfate a popular pump-inducing ingredient, but further research is needed on this ingredient (21,22). 1-Amino-4-guanidinobutane sulfate salt, 4-Guanidinobutylamine sulfate salt, N-(4-Aminobutyl)guanidine sulfate salt. I prefer cit mal over agmatine personally, but you can stack both. I e been through real opiate withdrawal (dilaudid) so I know the signs and feelings. or s. Gorilla Mode Pre-workout Cost. Agmatine Sulfate is another ingredient that needs more research, however, the theory is that it can help boost nitric oxide in the body, and increase muscular pumps. Hooligan is the strongest pre workout without banned substances, bar none. Agmatine Sulfate (as Agmass™) is naturally produced in our bodies and is very important with reducing pain, lowering. Lot of work has to go into it, be nice to see users exchanging there best usage of agmatine to help understand it more. Gilad and his. Agmatine is one of the most fascinating, and beneficial, substances. Dosage Examine Database Refer and Earn Agmatine is most often used for Pain. I was also a heavy kratom user and have been off it now for 39 days. : H55363 CAS-No 2482-00-0 Synonyms No information available Recommended Use Laboratory chemicals. Serious Nutrition Solutions. The registration samples provided tested positive for high levels of Methylhexanamine, a banned stimulant. More and more chemicals have been getting banned without any explanation and there's no reason for the trend. Since agmatine is able to block NMDA receptors, and ketamine, like agmatine, also shows an antidepressant action, abuse-related side effects may occur following pharmacological interference with the agmatinergic system. Think it's banned in Europe but I managed buy some online and it made it through to me. 500 g) and lithium hydroxide (0. Sulfate allergies are rare. The UK 14 304 was. Hi there. Most of the research has been focused on it treatment for neuropathy and other nerve disorders. Awards 3. Agmatine sulfate (40 mg/kg, twice daily) was given to the agmatine groups orally for 8 weeks. C) Ethanol intake (g/kg) for male mice that received pretreatment with different doses of agmatine during Test Cycle 4 (second cycle of treatment) (N = 11–12/group). I would take them 3 times a day everyday (that was the plan) Day 1: Sunday June 9th, 2019. While many studies point out that Agmatine reduces NOS, it appears to be a regulator rather than something that acutely lowers or increases concentrations. It quickly became popular for its similarities to banned substances such as Ephedrine, DMAA, and AMP-Citrate. It can help to improve blood flow, increase muscle pumps, and reduce muscle fatigue. The supplement may be able to offer similar short-term pain relief (x). v18. This makes agmatine sulfate a popular pump-inducing ingredient, but further research is necessary. Join the. Agmatine Sulfate (as Agmass™) 600 mg. Giggling during disassociation, whether induced by drugs, mediation. Molecular Formula CHNOS. It is made from the amino acid known as arginine. It also relives pain and can heal stomach ulcers. It can help to improve blood flow, increase muscle pumps, and reduce muscle fatigue. It shows promise for alleviating neuropathic pain and drug addiction and shows some potential in protecting against strokes and benefitting cognitive health. However,. While agmatine sulfate appears to be generally safe, there. And if you take a lot of amino acids, they'll be competing for absorption, so maybe keep that in mind on your journey. This effect could be due either to a central action of agmatine (a clonidine displacing substance. Yes, in my experience, Agmatine is likely to synergize and and potentiate cannabis (and probably other drugs as well). Description. com. I think. injury recovery: Rats heal faster after face is dissected. But for hypotensive people it's a different story. When i started taking agmatine my level of agony went from a 10 to a 4. Bulk Supplements offers an Agmatine Sulfate that builds muscles with Nitric Oxid. It may also have anti-inflammatory and neuroprotective effects. Have been taking agmatine for 2 months. Thanks, but that doesn’t really pertain to the question I’m asking. , shampoo, toothpaste, shaving foam, body washes and facial cleansers). In 2 studies of 61 participants with a herniated lumbar disk, agmatine supplementation for 10 days reduced pain and improved quality of life []. Agmatine, a product of arginine decarboxylation, was first discovered in mammalian brain in 1994 (). Agmatine, locally synthesized, is an endogenous agonist at imidazoline receptors, a noncatecholamine ligand at alpha 2-adrenergic receptors and may act as a neurotransmitter. Far Beyond Driven may contain ingredients that are banned by some sports organizations and/or increase risk of false positive on a drug. Agmantine is a natural metabolite of the amino acid arginine. Agmatine experience. 9936 g) were added with stirring, and the resultant mixture was left standing for another 120 h, as described above, and then diluted with water, acidified to pH 5 with hydrochloric acid, and ultrafiltered through a membrane with a nominal molecular weight cutoff value of. Agmatine Sulfate – Bulk Supplements. Agmatine is known to cross the blood brain barrier where 10, 50, and 300mg/kg injections of agmatine into mice noted that the highest dose was able to increase neural agmatine to approximately 800ng/g (700% higher than baseline) and in monkeys injected with 25-200mg/kg agmatine it was found that the rise in cerebral agmatine (11. Agmatine sulfate salt has been used: to study its effects on nod-like receptor protein 3 (NLRP3) inflammasome activation and cytokine responses in sub-chronic restraint stress rat models; as an N-methyl-D-aspartate (NMDA) receptor blocker to study its therapeutic effects on autistic behaviors in the valproic acid-induced animal model of autism; as a standard. My anhedonia was induced by a combination of depression, anxiety and chronic use of stimulants (ritalin, piracetam etc) and antidepressants (ssris and snris). Also it‘s used for many substances and drugs for tolerance, withdrawal and potentiation. Lithium orotate is an orotic acid that has become a popular nootropic supplement because it is so effective at treating anxiety, panic disorder, Alzheimer's disease, and depression. Agmatine is supposed to be great for brain health which makes sense. 6-6. Hooligan is brimming with pump, energy, and focus ingredients to keep you going all day long. H2N(CH2)4NHC(=NH)NH2·H2SO4. TL/DR at the bottom. BP and BS RTF at 85% 5RM, CMVJ, Treadmill Sprint Test:. 9% saline. I’ve had lots of battles stabilizing my blood pressure over the past few years, and I’ve come to the conclusion that agmatine actually raises it 10-15 points both systolic and diastolic. Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme. I use agmatine sulfate to potentiate kratom and CBD, and it works well for me. But yeah size 000 capsules. Strayed at low doses felt zero effect then upped to my current dose and also feel zeroish effect. According to some scientists, the chemical. Agmatine binds with high affinity to α2-adrenergic receptors and imidazoline binding sites and produces blockade of the NMDA-receptor associated cation channels. Only recently has the demonstration of agmatine biosynthesis in mammals revived research, indicating its exceptional modulatory action at multiple molecular. Most human-based testing has utilized 2. 5g morning empty stomach and 1. Agmatine induces gastric protection against ischemic injury by reducing vascular permeability in rats, doi: 10. New comments cannot be posted and votes cannot be cast. This thread is archived. The side effects increase when other stimulants. This ingredient is a popular addition to many pre-workout and intra-workout supplements due to its effective power to enhance muscle pumps and improve the vascularity that gives that envied swole look. Agmatine Sulfate is the supplemental form of Agmatine. My anxiety and rumination are almost completely gone. I take 1. Creatine HCl: 200 mg. Glutamate is good for thinking and learning, but in excess, it causes anxiety and ruminating thoughts that feel loud while we try to sleep. Take an extra serving while exercising for best results. Agmatine sulfate banned – (Image Source: Pixabay. At present, the industrial production of agmatine mainly depends on the chemical method, but it is often accompanied by problems including cumbersome processes, harsh reaction conditions, toxic substances production and heavy environmental pollution. Beta Alanine, Betaine Anhydrous, Agmatine Sulfate, L-Tyrosine, Lion’s Mane Mushroom,. Sports. 6g. It‘s said that Agmatine is banned in Europe but does that also mean that the owning of Agmatine and bringing it with over border is illegal too? I‘d be very happy about more information. As usual. Then I became a wizard. 27. The very empty stomach has to be it. OUR QUALITY: Our products are manufactured in a CGMP certified facility. Basically the way it works is Bromantane upregulates L-Tyrosine hydroxylase, the enzyme that breaks down L-Tyrosine into dopamine, thus giving you more dopamine. I have taken agmatine after kratom and I got a slight warm feeling, it's all about getting the right dose and how often extra. It is a salt form of agmatine discovered back in the early 1900s. While agmatine sulfate appears to be generally safe, there. But is ok to buy, but not to sell. November 2016 . Dávkovanie. MADE IN THE USA. Tried everything, benzos, f-phenibut, Kratom, kava, etc. Creatine or arginine is most popular. According to several reports and studies, agmatine naturally reverses pain from factors like inflammation, neuropathy and spinal cord injury. SNS Agmatine Powder contains 1000 mg (1 gram) of Agmatine per scoop. Alternatively, you can use the ‘toss and wash’ method. p. I believe 1g Creatine nitrate is around 321mg nitrate while arginine is around 262mg. Six months later, oral agmatine sulfate (25 mg/kg, bid) or placebo (hydroxypropyl methylcellulose, bid) was administered to the same dogs for 28 days with a 2 week washout period between treatments. ALLMAX makes an "essentials" line, which are high quality, single ingredient products, at cost effective prices. p. Agmatine long-term safety: Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report. Energy: 934kJ/223kcal. Government Chemist Strategy 2017 - 2020 . i18. For a lot of drugs the dosing regimen is. Clinical trials indicate the safety and effectiveness of short-term (up to 21 days) high dose regimens of oral agmatine sulfate, but longer term studies are lacking. IMPORTANT! Agmatine Sulphate for quitting phenibut. It negates depressive behaviour by protecting brain cells from high levels of stress hormone cortisol. During the treatment interval, only three participants reported mild-to-moderate adverse effects . 1. Agmatine Sulfate is a biogenic amine derived from the amino acid L-Arginine. £59. Agmatine sulfate is the sulfate preparation of Agmatine, the decarboxylated form of L-arginine and an endogenous metabolic product highly conserved across life forms. Agmatine sulfate salt has been used: to study its effects on nod-like receptor protein 3 (NLRP3) inflammasome activation and cytokine responses in sub-chronic restraint stress rat models; as an N-methyl-D-aspartate (NMDA) receptor blocker to study its therapeutic effects on autistic behaviors in the valproic acid-induced animal model of autism; as a standard. Well ofc it will give you bad side effects is you just google agmatine sulphate max daily dose you will see that The standard dose is 2-3g of agmatine sulfate per day. Given that agmatine sulfate is one of the more expensive ingredients in these preworkout blends, we’ll use $0. The results suggest that dietary agmatine sulfate has a significant effect in reducing neuropathic pain intensity associated with painful SFN resistant to treatment. xd169 • 5 mo. Agmatine Sulfate. The funny thing is that you can still buy DMAA and DMHA online. Agmatine, a natural polyamine produced from arginine by arginine decarboxylase, was first discovered in 1910, but its physiological significance was disregarded for a century. Manufacturers, wholesalers and sellers must ensure any herbal products they place on the market do not contain banned ingredients. Earn Rewards On Everything; Unbeatable Deals; Free Shipping On $99+ Money Back Guarantee;. 6 to 6. Jack_Strident • 3 yr. Agmatine treatment also attenuates motor function deficits and tissue damage after traumatic brain or spinal cord injuries in animal models 78, 82, 83, 84. Agmatine and methamphetamine were dissolved in 0. They are man-made only and have been manufactured for over 50 years. It also has research for depression, and some use it as a nootropic for focus and cognitive function. Agmatine 500mg every 6 hours. What has been banned in the United States are the active alkaloid compounds found within the Ephedra plant, ephedrine and. At present, the industrial production of agmatine mainly depends on the chemical method, but it is often accompanied by problems including cumbersome processes, harsh reaction conditions,.